By David I. Bernstein, Moira Chan-Yeung, Jean-Luc Malo, I. Leonard Bernstein
Addressing each key portion of occupational asthma-including affliction mechanisms, medical analysis, therapy, and different types of causative agents-this 3rd version offers knowledgeable survey of the main influential advances and learn within the box. delivering new and elevated chapters on genetics, environmental tracking, pathophysiology, dermis and pulmonary interactions, and the surveillance and prevention of occupational bronchial asthma, this consultant will stand on my own because the most modern resource at the subject.
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Extra resources for Asthma in the Workplace, Third Edition
Symptoms and functional evidence of partially reversible obstructive airﬂow limitation occur after exposure to grain dusts or in workers of aluminum potrooms (Chapter 23). There is also evidence that exposure to inorganic dusts such as silica and silicon carbide causes airway obstruction with some reversibility and bronchial hyperresponsiveness (Chapter 28) (18,19). In another condition, eosinophilic bronchitis, there is evidence of eosinophilic airway inﬂammation but without evidence of reversible airway obstruction or bronchial hyperresponsiveness, which may represent a preasthmatic state.
Petran M, Cocarla A, Baiescu M. Association between bronchial hyper-reactivity and exposure to silicon carbide. Occup Med 2000; 50:103–106. K. I. A. Editors’ Note: In the ﬁrst and second editions of Asthma in the Workplace, this chapter was coauthored by Drs. Jack Pepys and I. Leonard Bernstein. Dr. Pepys’ contribution was the ‘‘Introduction’’ through the section entitled ‘‘Simulated Occupational Provocation Tests,’’ which the editors decided to retain in toto for this issue. This section includes a review of some of Dr.
20 Pepys and Bernstein Figure 7 Occupational-type test in Figure 5 with mixture of 10 g of puriﬁed commercial ampicillins in 250 g lactose in same patients as Figure 3. (–), lactose control; (– –), lactose plus commercial unpuriﬁed ampicillin; (–Á–), lactose plus puriﬁed ampicillin; (ÁÁÁÁÁ), lactose plus another puriﬁed ampicillin. Note: Late, reproducible three- to four-hour onset asthmatic reactions to puriﬁed and unpuriﬁed ampicillins, more severe than 6APA reactions (Fig. 3) and attributable to addition of phenyl-glycine to 6APA nucleus to form ampicillin.