By Plamen Demirev, Todd R. Sandrin
In the final region century, advances in mass spectrometry (MS) were on the vanguard of efforts to map complicated organic structures together with the human metabolome, proteome, and microbiome. All of those advancements have allowed MS to turn into a well-established molecular point know-how for microorganism characterization. MS has confirmed its enormous virtue as a swift, exact, and most economical procedure for microorganism id, in comparison to traditional phenotypic ideas. within the final numerous years, purposes of MS for microorganism characterization in examine, scientific microbiology, counter-bioterrorism, nutrients safeguard, and environmental tracking were documented in hundreds of thousands of courses. Regulatory our bodies in Europe, the U.S., and somewhere else have licensed MS-based assays for infectious affliction diagnostics. As of mid-2015, greater than 3300 advertisement MS structures for microorganism id were deployed world wide in hospitals and scientific labs.
While past paintings has coated broader methods in utilizing MS to signify microorganisms on the species point or above, this e-book makes a speciality of strain-level and subtyping purposes. In twelve person chapters, innovators, leaders and practitioners within the box from around the globe have contributed to a entire assessment of present and next-generation ways for MS-based microbial characterization on the subspecies and pressure degrees. Chapters comprise updated reference lists in addition to web-links to databases, suggested software program, and different worthwhile tools.
The emergence of recent, antibiotic-resistant lines of human or animal pathogens is of striking situation not just to the medical and clinical groups, yet to most people besides. advancements of novel MS-based assays for speedy identity of traces of antibiotic-resistant microorganisms are reviewed within the publication in addition. Microbiologists, bioanalytical scientists, infectious illness experts, scientific laboratory and public health and wellbeing practitioners in addition to researchers in universities, hospitals, govt labs, and the pharmaceutical and biotechnology industries will locate this publication to be a well timed and useful source.
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Additional info for Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance
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