Download Applications of Mass Spectrometry in Microbiology: From by Plamen Demirev, Todd R. Sandrin PDF

By Plamen Demirev, Todd R. Sandrin

In the final region century, advances in mass spectrometry (MS) were on the vanguard of efforts to map complicated organic structures together with the human metabolome, proteome, and microbiome. All of those advancements have allowed MS to turn into a well-established molecular point know-how for microorganism characterization. MS has confirmed its enormous virtue as a swift, exact, and most economical procedure for microorganism id, in comparison to traditional phenotypic ideas. within the final numerous years, purposes of MS for microorganism characterization in examine, scientific microbiology, counter-bioterrorism, nutrients safeguard, and environmental tracking were documented in hundreds of thousands of courses. Regulatory our bodies in Europe, the U.S., and somewhere else have licensed MS-based assays for infectious affliction diagnostics. As of mid-2015, greater than 3300 advertisement MS structures for microorganism id were deployed world wide in hospitals and scientific labs.

While past paintings has coated broader methods in utilizing MS to signify microorganisms on the species point or above, this e-book makes a speciality of strain-level and subtyping purposes. In twelve person chapters, innovators, leaders and practitioners within the box from around the globe have contributed to a entire assessment of present and next-generation ways for MS-based microbial characterization on the subspecies and pressure degrees. Chapters comprise updated reference lists in addition to web-links to databases, suggested software program, and different worthwhile tools.

The emergence of recent, antibiotic-resistant lines of human or animal pathogens is of striking situation not just to the medical and clinical groups, yet to most people besides. advancements of novel MS-based assays for speedy identity of traces of antibiotic-resistant microorganisms are reviewed within the publication in addition. Microbiologists, bioanalytical scientists, infectious illness experts, scientific laboratory and public health and wellbeing practitioners in addition to researchers in universities, hospitals, govt labs, and the pharmaceutical and biotechnology industries will locate this publication to be a well timed and useful source.

Show description

Read Online or Download Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance PDF

Similar epidemiology books

Applied Statistical Genetics with R: For Population-based Association Studies (Use R!)

The large array of molecular point info now on hand provides fascinating possibilities to signify the genetic underpinnings of advanced ailments whereas studying novel organic pathways to ailment development. during this introductory graduate point textual content, Dr. Foulkes elucidates middle strategies that undergird the wide variety of analytic concepts and software program instruments for the research of information derived from population-based genetic investigations.

Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

The 1st version of Human Genome Epidemiology, released in 2004, mentioned how the epidemiologic method offers a major clinical starting place for learning the continuum from gene discovery to the improvement, functions and review of human genome details in enhancing healthiness and combating illness.

Reducing Poverty Through Growth And Social Policy Reform in Russia (Directions in Development)

Following the 1998 monetary challenge, 4 out of each ten humans slipped into poverty, unable to fulfill easy wishes. fortunately, post-crisis financial rebound was once notable and broad-based - albeit asymmetric - throughout sectors and areas. This name explores the character of poverty, either nationally and domestically, to spot the teams with a excessive poverty probability.

International Health and Aid Policies: The Need for Alternatives

Overseas well-being and reduction rules of the previous twenty years have had an immense effect at the supply of care in low and middle-income international locations. This ebook argues that those regulations have frequently did not in attaining their major goals, and feature actually contributed to constrained entry to relatives drugs and health facility care.

Additional info for Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance

Example text

References Aguilar M-I. HPLC of peptides and proteins: methods and protocols. Totowa: Humana Press; 2004. Alatoom AA, Cunningham SA, Ihde SM, Mandrekar J, Patel R. Comparison of direct colony method versus extraction method for identification of gram-positive cocci by use of bruker biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol. 2011;49(8):2868–73. Alvarez MTB, Shah DJ, Thulin CD, Graves SW. Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach.

Anal Chem. 1975:47(2):219–25. Basile F. Rapid sample preparation for microorganism analysis by mass spectrometry. In Fenselau C, Demirev P, Editors. Rapid characterization of microorganisms by mass spectrometry. ACS symposium series; American Chemical Society: Washington, DC.  1065. 2011. pp 5–34. Basile F, Ferrer I, Furlong ET, Voorhees KJ. Simultaneous multiple substrate tag detection with ESIIon trap MS for in vivo bacterial enzyme activity profiling. Anal Chem. 2002;74(16):4290–3. Basile F, Kassalainen GE, Ratanathanawongs Williams SK.

New Jersey: Wiley; 2008.  6–8. Bruins AP. Mechanistic aspects of electrospray ionization. J Chromatogr A. 1998;794(1):345–57. Burckhardt I, Zimmermann S. 5 hours. J Clin Microbiol. 2011;49:3321–4. Calderaro A, Piccolo G, Montecchini S, Buttrini M, Gorrini C, Rossi S, Arcangeletti MC, De Conto F, Medici MC, Chezzi C. MALDI-TOF ms analysis of human and animal Brachyspira species and benefits of database extension. J. Proteomics. 2013;78:273–80. Calderaro A, Piccolo G, Gorrini C, Montecchini S, Buttrini M, Rossi S, Piergianni M, De CF, Arcangeletti MC, Chezzi C, Medici MC.

Download PDF sample

Rated 4.20 of 5 – based on 33 votes